反应详情

To a solution of (R)-benzyl 4-(dimethylamino)-3-(5-(m-tolylethynyl)thiophene-2-sulfonamido)butanoate (25 mg, 0.05 mmol) and methyl iodide (100 μL, 40 eq) in CH2Cl2 (1 mL) was stirred overnight at room temperature. The solution was concentrated to give the title compound in quantitative yield. MS ESI 511.3 [M]+, calcd for [C27H31N2O4S2]+ 511.17.

1. concentrationThe solution was concentrated