1,4-Dioxa-8-azaspiro(4.5)decane → HCID 20782267, compound

HRID 1959083Notes

Reaction equation

HRID 1959083 reaction equation
[O:1]1[C:5]2([CH2:10][CH2:9][NH:8][CH2:7][CH2:6]2)[O:4][CH2:3][CH2:2]1.[S:11](N)([NH2:14])(=[O:13])=[O:12]>O1CCOCC1>[O:1]1[C:5]2([CH2:10][CH2:9][N:8]([S:11]([NH2:14])(=[O:13])=[O:12])[CH2:7][CH2:6]2)[O:4][CH2:3][CH2:2]1

Participants

4

Reactant 2

HCID 674351,4-Dioxa-8-azaspiro(4.5)decaneHCID 82267Sulfamide

Product 1

HCID 20782267HCID 20782267, compound

Reagents, catalysts & solvents 1

HCID 312751,4-DioxaneSolvent

Procedure

A solution of 1,4-dioxa-8-aza-spiro[4.5]decane (2 mL) and sulfamide (1.65 g) in 1,4-dioxane (28 mL) was heated at reflux for 48 h, then the volatiles were evaporated to afford the title compound as a pale yellow solid. Yield: 3.4 g

Workup

  1. temperatureat reflux for 48 h
  2. customthe volatiles were evaporated

Sources & evidence

ORD record
ord-41cfb53f9d0140be8419c1c8e266f2fb
Source dataset
uspto-grants-2013_04
Patent number
US08410123B2

Reaction notes

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