Hydrochloric Acid → HCID 59443085, compound
Reaction equation
[Cl:1][C:2]1[CH:3]=[CH:4][C:5](/[C:9](/[C:16]2[CH:21]=[CH:20][C:19]([F:22])=[CH:18][CH:17]=2)=[C:10](/[F:15])\[C:11](O)([CH3:13])[CH3:12])=[C:6]([OH:8])[CH:7]=1.Cl>>[Cl:1][C:2]1[CH:7]=[C:6]2[C:5]([C:9]([C:16]3[CH:21]=[CH:20][C:19]([F:22])=[CH:18][CH:17]=3)=[C:10]([F:15])[C:11]([CH3:13])([CH3:12])[O:8]2)=[CH:4][CH:3]=1Participants
3
Procedure
The compound obtained in (4) described above (314 mg) and concentrated hydrochloric acid (4 mL) were treated in the same manner as Reference Example 5(3) to give the titled compound (132 mg) as a colorless powder.
Sources & evidence
- ORD record
- ord-323463e6cfcc41e18366ba82a42e7221
- Source dataset
- uspto-grants-2013_04
- Patent number
- US08410166B2
Reaction notes
Loading…