HCID 59443055, compound → HCID 59443022, compound

HRID 1959135Notes

Reaction equation

HRID 1959135 reaction equation
Br[C:2]1[C:3]([CH3:21])([CH3:20])[O:4][C:5]2[C:10]([C:11]=1[C:12]1[CH:17]=[CH:16][C:15]([F:18])=[CH:14][CH:13]=1)=[CH:9][CH:8]=[C:7]([Cl:19])[CH:6]=2>C([Sn](CCCC)(CCCC)C=C)CCC>[Cl:19][C:7]1[CH:6]=[C:5]2[C:10]([C:11]([C:12]3[CH:17]=[CH:16][C:15]([F:18])=[CH:14][CH:13]=3)=[C:2]([C:3]([O:4][CH2:5][CH3:6])=[CH2:2])[C:3]([CH3:21])([CH3:20])[O:4]2)=[CH:9][CH:8]=1

Participants

3

Reactant 1

HCID 59443055HCID 59443055, compound

Product 1

HCID 59443022HCID 59443022, compound

Reagents, catalysts & solvents 1

HCID 81998TributylvinyltinSolvent

Procedure

A mixture of 3-bromo-7-chloro-4-(4-fluorophenyl)-2,2-dimethyl-2H-chromen (a compound obtained in Reference Example 8(1); 220 mg) and tributyl(vinyl)tin (405 μL) were treated in the same manner as Reference Example 11(1) to give the titled compound (144 mg) as a pale yellow powder.

Workup

  1. customobtained in Reference Example 8(1)

Sources & evidence

ORD record
ord-11e4e74636094b1a8ee1a8639dc53baf
Source dataset
uspto-grants-2013_04
Patent number
US08410166B2

Reaction notes

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