Dichloromethane → HCID 178491574, compound

HRID 195918Notes

Reaction equation

[Cl:48][CH2:49][Cl:50].[F:1][c:2]1[cH:3][c:4]([NH:8][CH:9]2[CH2:10][CH2:11][N:12]([C:15]([CH2:16][c:17]3[cH:18][c:19]([O:38][CH3:39])[c:20]([CH2:23][N:24]4[CH2:25][CH:26]([CH3:37])[N:27]([C:30]([O:31][C:32]([CH3:33])([CH3:34])[CH3:35])=[O:36])[CH2:28][CH2:29]4)[cH:21][cH:22]3)=[O:40])[CH2:13][CH2:14]2)[cH:5][cH:6][cH:7]1.[F:41][C:42]([F:43])([F:44])[C:45]([OH:46])=[O:47]>>[F:1][c:2]1[cH:3][c:4]([NH:8][CH:9]2[CH2:10][CH2:11][N:12]([C:15]([CH2:16][c:17]3[cH:18][c:19]([O:38][CH3:39])[c:20]([CH2:23][N:24]4[CH2:25][CH:26]([CH3:37])[NH:27][CH2:28][CH2:29]4)[cH:21][cH:22]3)=[O:40])[CH2:13][CH2:14]2)[cH:5][cH:6][cH:7]1

Participants

Reactant 3

HCID 6344Dichloromethane

HCID 6422Trifluoroacetic acid

HCID 178491575tert-butyl 4-[[4-[2-[4-(3-fluoroanilino)piperidin-1-yl]-2-oxoethyl]-2-methoxyphenyl]methyl]-2-methylpiperazine-1-carboxylate

Product 1

HCID 178491574HCID 178491574, compound

Sources & evidence

ORD record: ord-ff0e290b767a484dac80c81b66e2446f
Source dataset: Training data from https://doi.org/10.1039/C8SC04228D (6/10)
DOI: 10.1039/C8SC04228D

Reaction notes

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