Participants
| Role | Name | HCID | Charge |
|---|
| Reactant | Water | HCID 962 | — |
| Reactant | Sodium ethoxide | HCID 2723922 | — |
| Reactant | 3-Aminobenzene-1-carboximidamide--hydrogen chloride (1/2) | HCID 3084651 | — |
| Reactant | 3-Amino-6-bromopyrazine-2-carbohydrazide | HCID 58070256 | — |
| Solvent | Dimethylformamide | HCID 6228 | — |
| Product | HCID 178507534 | HCID 178507534 | 100% |
Reaction Steps
A mixture of 3-amino-6-bromo-pyrazine-2-carbohydrazide (5 g, 21.55 mmol), 3-aminobenzamidine dihydrochloride (4.484 g, 21.55 mmol) and NaOEt (4.399 g, 64.65 mmol) were combined in DMF (50.00 mL) and heated to 100° C. in the microwave for 20 min. Water was added and the precipitate collected. Used without further purification. Assumed 100% Yield.
Provenance & Evidence
| DOI | 10.6084/m9.figshare.5104873.v1 |
|---|
| Patent number | US08410112B2 |
|---|
| Source dataset | uspto-grants-2013_04 |
|---|
| ORD ID | ord-c8ec119755e74a39a12cbe4979f73bc0 |
|---|
| Source note | uspto-grants-2013_04 |
|---|
