HuagongsheHuagongshe Chemistry Print Report · For research reference only
3-(5-Fluoro-2-methoxy-phenylamino)-but-2-enoic acid ethyl ester → HCID 178491787, compound
Participants
| Role | Name | HCID | Charge |
|---|---|---|---|
| Reactant | 3-(5-Fluoro-2-methoxy-phenylamino)-but-2-enoic acid ethyl ester | HCID 67078042 | — |
| Solvent | Diphenyl Ether | HCID 7583 | — |
| Solvent | Hexane | HCID 8058 | — |
| Product | HCID 178491787 | HCID 178491787 | — |
Reaction Steps
A solution of 3-(5-fluoro-2-methoxy-phenylamino)-but-2-enoic acid ethyl ester (1.8 g, 6.7 mmol) in diphenyl ether (10.7 mL) was heated to 250° C. for 25 min. The reaction mixture was cooled to room temperature, diluted with hexane, and filtered to give the title compound. MS (m/z): 208.1 [M+H+].
Provenance & Evidence
| DOI | 10.6084/m9.figshare.5104873.v1 |
|---|---|
| Patent number | US08410134B2 |
| Source dataset | uspto-grants-2013_04 |
| ORD ID | ord-f48f5265a5924725b2420533940429ad |
| Source note | uspto-grants-2013_04 |