反应详情

A solution of 3-(5-fluoro-2-methoxy-phenylamino)-but-2-enoic acid ethyl ester (1.8 g, 6.7 mmol) in diphenyl ether (10.7 mL) was heated to 250° C. for 25 min. The reaction mixture was cooled to room temperature, diluted with hexane, and filtered to give the title compound. MS (m/z): 208.1 [M+H+].

1. filtrationfiltered