Back
HuagongsheHuagongshe Chemistry Print Report · For research reference only
HRID 1959584Generated: November 4, 2026

Potassium tert-butoxide → HCID 44190365, compound

https://huagongshe.com/reaction/1959584

Reaction equation

Participants

RoleNameHCIDCharge
ReactantPotassium tert-butoxideHCID 23665647—
ReactantHCID 44190364HCID 44190364—
Solvent1,4-DioxaneHCID 31275—
ProductHCID 44190365HCID 44190365—

Reaction Conditions

Temperature100 °C

Reaction Steps

Potassium tert-butylate (1.77 g, 15.80 mmol) was added to a stirred solution of 3,5-dichloro-4-(tetrahydro-pyran-2-yloxymethyl)-pyridine (825 mg, 3.16 mmol) in dioxane. After stirring for 3 d at 100° C. the solvent was removed in vacuo. The resulting title compound was used for the next reaction without purification. MS (m/z): 243.8 [M+H+].

Provenance & Evidence

DOI10.6084/m9.figshare.5104873.v1
Patent numberUS08410134B2
Source datasetuspto-grants-2013_04
ORD IDord-ab3b9aa7343b42c289b5cedf45898f18
Source noteuspto-grants-2013_04