反应详情

Coupling of 4-bromo-2-methyl-quinolin-8-ol (75 mg. 0.32 mmol) with 1-methyl-1H-pyrrole-2-carbonitrile (84 mg. 0.79 mmol) according to the synthesis of of 2-methyl-4-(1-methyl-1H-imidazol-2-yl)-quinolin-8-ol using LDA as the base (1.8 M in Heptan/THF/Ethylbenzol. 0.44 mL. 0.79 mmol) yielded the title compound. MS (m/z): 264.2 [M+H+].