Methanol → 1-[6-(3-Dimethylamino-pyrrolidin-1-yl)-4-(4-methanesulfonyl-phenyl)-2-methyl-quinolin-3-yl]-2,2,2-trifluoro-ethanone
Reaction equation
[Br:1][c:2]1[cH:3][c:4]2[c:5](-[c:19]3[cH:20][cH:21][c:22]([S:25](=[O:26])(=[O:27])[CH3:28])[cH:23][cH:24]3)[c:6]([C:13]([C:14]([F:15])([F:16])[F:17])=[O:18])[c:7]([CH3:12])[n:8][c:9]2[cH:10][cH:11]1.[C:39]([O:40][CH2:41][CH3:42])(=[O:43])[CH3:44].[CH3:29][N:30]([CH:31]1[CH2:32][NH:33][CH2:34][CH2:35]1)[CH3:36].[CH3:37][OH:38]>>[c:2]1([N:33]2[CH2:32][CH:31]([N:30]([CH3:29])[CH3:36])[CH2:35][CH2:34]2)[cH:3][c:4]2[c:5](-[c:19]3[cH:20][cH:21][c:22]([S:25](=[O:26])(=[O:27])[CH3:28])[cH:23][cH:24]3)[c:6]([C:13]([C:14]([F:15])([F:16])[F:17])=[O:18])[c:7]([CH3:12])[n:8][c:9]2[cH:10][cH:11]1Participants
5
Reactant 4
Product 1
Sources & evidence
- ORD record
- ord-8c3a8b66c8be4a109dec430a2878127c
- Source dataset
- Training data from https://doi.org/10.1039/C8SC04228D (6/10)
Reaction notes
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