HuagongsheHuagongshe Chemistry Print Report · For research reference only
Morpholine → 2-[4-(Morpholin-4-ylcarbonyl)phenoxy]ethanol
Participants
| Role | Name | HCID | Charge |
|---|---|---|---|
| Reactant | Morpholine | HCID 8083 | — |
| Reactant | Benzoic acid, 4-(2-hydroxyethoxy)-, methyl ester | HCID 76670 | — |
| Product | 2-[4-(Morpholin-4-ylcarbonyl)phenoxy]ethanol | HCID 66730549 | 27% |
Reaction Steps
Using morpholine (1.25 mL, 14.3 mmol) and methyl 4-(2-hydroxyethoxy)benzoate (1.00 g, 5.10 mmol), the desired title compound (345 mg, yield 27%) was obtained by the same method as in Reference Example 8.
Provenance & Evidence
| DOI | 10.6084/m9.figshare.5104873.v1 |
|---|---|
| Patent number | US08410273B2 |
| Source dataset | uspto-grants-2013_04 |
| ORD ID | ord-3991bf5149c74af09cf4abe35fcafc67 |
| Source note | uspto-grants-2013_04 |