Isopropylethanediol → 2-[4-(2-Isopropoxyethoxy)phenyl]-4,4,5,5-tetramethyl-1,3,2-dioxaborolane

HRID 1959969Notes

Reaction equation

[CH3:1][C:2]1([CH3:16])[C:6]([CH3:8])([CH3:7])[O:5][B:4]([C:9]2[CH:14]=[CH:13][C:12]([OH:15])=[CH:11][CH:10]=2)[O:3]1.[CH:17]([O:20][CH2:21][CH2:22]O)([CH3:19])[CH3:18]>>[CH:17]([O:20][CH2:21][CH2:22][O:15][C:12]1[CH:13]=[CH:14][C:9]([B:4]2[O:3][C:2]([CH3:16])([CH3:1])[C:6]([CH3:7])([CH3:8])[O:5]2)=[CH:10][CH:11]=1)([CH3:19])[CH3:18]

Participants

Reactant 2

HCID 7996Isopropylethanediol

HCID 27346244-(4,4,5,5-Tetramethyl-1,3,2-dioxaborolan-2-yl)phenol

Product 1

HCID 667304212-[4-(2-Isopropoxyethoxy)phenyl]-4,4,5,5-tetramethyl-1,3,2-dioxaborolaneYield 31%

Procedure

Using 4-(4,4,5,5-tetramethyl-1,3,2-dioxaborolan-2-yl)phenol (609 mg, 2.76 mmol) and ethylene glycol monoisopropyl ether (432 mg, 4.15 mmol), the desired title compound (100 mg, yield 31%) was obtained by the same method as in Example 2 (2a).

Sources & evidence

ORD record: ord-a6d68013bf914849ae53afb8952dbd53
Source dataset: uspto-grants-2013_04
DOI: 10.6084/m9.figshare.5104873.v1
Patent number: US08410273B2

Reaction notes

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