Dimethylamine, hydrochloride → HCID 66730441, compound

HRID 1959970Notes

Reaction equation

HRID 1959970 reaction equation
[O:1]1[C:6]2([CH2:11][CH2:10][O:9][CH2:8][CH2:7]2)[C:5](=[O:12])[O:4][CH2:3][CH2:2]1.Cl.[CH3:14][NH:15][CH3:16]>>[OH:4][CH2:3][CH2:2][O:1][C:6]1([C:5]([N:15]([CH3:16])[CH3:14])=[O:12])[CH2:11][CH2:10][O:9][CH2:8][CH2:7]1

Participants

3

Reactant 2

HCID 10473Dimethylamine, hydrochlorideHCID 66730473HCID 66730473, compound

Product 1

HCID 66730441HCID 66730441, compoundYield 99%

Procedure

Using 1,4,9-trioxaspiro[5.5]undecane-5-one produced in Reference Example 15 (15a) and dimethylamine hydrochloride (659 mg, 8.14 mmol), the desired title compound (630 mg, yield 99%) was obtained by the same method as in Example 5.

Sources & evidence

ORD record
ord-0880acc3602a43f6b3071c063506a539
Source dataset
uspto-grants-2013_04
Patent number
US08410273B2

Reaction notes

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