Methyl iodide → HCID 178481204, compound

HRID 1959996Notes

Reaction equation

HRID 1959996 reaction equation
[C:1]([C:3]1[CH:8]=[CH:7][C:6]([N:9]2[C:13]3[CH:14]=[CH:15][CH:16]=[CH:17][C:12]=3[N:11]=[CH:10]2)=[CH:5][CH:4]=1)#[N:2].[CH3:18][I:19]>C1COCC1>[I-:19].[C:1]([C:3]1[CH:8]=[CH:7][C:6]([N+:9]2[C:13]3[CH:14]=[CH:15][CH:16]=[CH:17][C:12]=3[N:11]([CH3:18])[CH:10]=2)=[CH:5][CH:4]=1)#[N:2]

Participants

4

Reactant 2

HCID 6328Methyl iodideHCID 532845425699-95-0

Product 1

HCID 178481204HCID 178481204, compound

Reagents, catalysts & solvents 1

HCID 8028TetrahydrofuranSolvent

Conditions

Temperature
40 °C

Procedure

1-(4-Cyanophenyl)benzimidazole (90 g, slightly contaminated with mineral oil) together with THF (250 ml) is placed in a reaction vessel, admixed with methyl iodide (116 g, 0.82 mol) and maintained at 40° C. for 25.5 hours. The residue formed is filtered off, washed with ethanol and dried under reduced pressure. This gives 123 g of 1-(4-cyanophenyl)-3-methylbenzimidazolium iodide.

Workup

  1. customis placed in a reaction vessel
  2. customThe residue formed
  3. filtrationis filtered off
  4. washwashed with ethanol
  5. customdried under reduced pressure

Sources & evidence

ORD record
ord-2f4e76f853ef4e00946739dba124f0e5
Source dataset
uspto-grants-2013_04
Patent number
US08410280B2

Reaction notes

Loading…