Methyl iodide → 1-(2-Bromo-4-cyanophenyl)-3-methylimidazolium iodide

HRID 1960002Notes

Reaction equation

HRID 1960002 reaction equation
[Br:1][C:2]1[CH:7]=[C:6]([C:8]#[N:9])[CH:5]=[CH:4][C:3]=1[N:10]1[CH:14]=[CH:13][N:12]=[CH:11]1.[CH3:15][I:16]>O1CCCC1>[I-:16].[Br:1][C:2]1[CH:7]=[C:6]([C:8]#[N:9])[CH:5]=[CH:4][C:3]=1[N+:10]1[CH:14]=[CH:13][N:12]([CH3:15])[CH:11]=1

Participants

4

Reactant 2

HCID 6328Methyl iodideHCID 688544441-(2-Bromo-4-cyanophenyl)imidazole

Product 1

HCID 1784806631-(2-Bromo-4-cyanophenyl)-3-methylimidazolium iodide

Reagents, catalysts & solvents 1

HCID 8028TetrahydrofuranSolvent

Procedure

1-(2-Bromo-4-cyanophenyl)imidazole (5.4 g, 22 mmol, 1 eq) and methyl iodide (15.4 g, 109.0 mmol, 5 eq) are dissolved in tetrahydrofuran (50 ml) and stirred at room temperature for 16 hours. The precipitate formed is filtered off and washed with ethanol.

Workup

  1. customThe precipitate formed
  2. filtrationis filtered off
  3. washwashed with ethanol

Sources & evidence

ORD record
ord-d9074701d73846239a7becf84512bf10
Source dataset
uspto-grants-2013_04
Patent number
US08410280B2

Reaction notes

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