反应详情

温度

25 °C

To a solution of EtOH (20 mL), H2O (4 mL) and KOH (593 mg, 11 mmol) was added compound 13-3 (2.46 g, 8.8 mmol). CS2 (0.65 mL, 11 mmol) was then added and the suspension was heated to reflux for 2 h. The reaction mixture was cooled to 25° C., then 40 mL of H2O and 0.8 mL of acetic acid were added resulting in a tan precipitate. The precipitate was collected by vacuum filtration resulting in title compound 13-4, which required no further purification.

1. temperaturethe suspension was heated
2. temperatureto reflux for 2 h
3. customresulting in a tan precipitate
4. filtrationThe precipitate was collected by vacuum filtration