Sodium Chloride → HCID 69128686, compound

HRID 1960227Notes

Reaction equation

HRID 1960227 reaction equation
[C:1]1([N:7]=[C:8]([S:15][CH:16]([CH3:18])[CH3:17])[CH2:9][CH2:10][Si](C)(C)C)[CH:6]=[CH:5][CH:4]=[CH:3][CH:2]=1.C(=O)([O-])[O-].[K+].[K+].[Cl-].[Na+]>CO>[C:1]1([N:7]=[C:8]([S:15][CH:16]([CH3:17])[CH3:18])[CH2:9][CH3:10])[CH:6]=[CH:5][CH:4]=[CH:3][CH:2]=1

Participants

5

Reactant 3

HCID 5234Sodium ChlorideHCID 11430Potassium CarbonateHCID 69127194HCID 69127194, compound

Product 1

HCID 69128686HCID 69128686, compoundYield 92.7%

Reagents, catalysts & solvents 1

HCID 887MethanolSolvent

Procedure

Isopropyl N-phenyl-3-(trimethylsilyl)thiopropioimidate (1.6 g) was dissolved to methanol (50 ml), small amount of potassium carbonate was added thereto under ice-cooling, then stirred for minutes. The reaction solution was poured into aqueous solution of sodium chloride, and it was extracted with ethyl acetate. The organic layer was washed with water, dried and distilled off the solvent to obtain isopropyl N-phenyl-thiopropioimidate (1.1 g).

Workup

  1. additionwas added
  2. temperatureunder ice-cooling
  3. extractionwas extracted with ethyl acetate
  4. washThe organic layer was washed with water
  5. customdried
  6. distillationdistilled off the solvent

Sources & evidence

ORD record
ord-af8e608999a4405e81437515e8184791
Source dataset
uspto-grants-2013_04
Patent number
US08410316B2

Reaction notes

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