Diethyl Carbonate → 5-(Hydroxymethyl)-3-[4-(5-methyl-1,2,4-oxadiazol-3-yl)phenyl]-1,3-oxazolidin-2-one

HRID 196101Notes

Reaction equation

HRID 196101 reaction equation
[C:55](=[O:56])([O:57][CH2:58][CH3:59])[O:60][CH2:61][CH3:62].[CH2:1]([O:3][C:2]([CH:4]([N:5]1[CH2:6][CH2:7][NH:8][CH2:9][CH2:10]1)[CH2:11][C:12]([O:13][CH2:14][CH3:15])=[O:16])=[O:17])[CH3:18].[CH3:19][c:20]1[o:21][n:22][c:23](-[c:24]2[cH:25][cH:26][c:27]([NH2:28])[cH:29][cH:30]2)[n:31]1.[CH3:37][c:38]1[n:39][c:40](-[c:43]2[cH:44][cH:45][c:46]([NH:49][CH2:50][CH:51]([CH2:52][OH:53])[OH:54])[cH:47][cH:48]2)[n:41][o:42]1.[CH3:63][C:64]([CH3:65])([O-:66])[CH3:67].[O:32]1[CH2:33][CH:34]1[CH2:35][OH:36]>>[C:1]1(=[O:3])[N:49]([c:46]2[cH:45][cH:44][c:43](-[c:40]3[n:39][c:38]([CH3:37])[o:42][n:41]3)[cH:48][cH:47]2)[CH2:50][CH:51]([CH2:52][OH:53])[O:54]1

Participants

7

Reactant 6

HCID 7766Diethyl CarbonateHCID 11164GlycidolHCID 45749132-Methylpropan-2-olateHCID 181881764-(5-Methyl-1,2,4-oxadiazol-3-yl)anilineHCID 18423302Diethyl 2-piperazin-1-ylbutanedioateHCID 199561213-[4-(5-Methyl-1,2,4-oxadiazol-3-yl)anilino]propane-1,2-diol

Product 1

HCID 199561055-(Hydroxymethyl)-3-[4-(5-methyl-1,2,4-oxadiazol-3-yl)phenyl]-1,3-oxazolidin-2-one

Sources & evidence

ORD record
ord-11711048deaa4b9cb1dad8fa69514d08
Source dataset
Training data from https://doi.org/10.1039/C8SC04228D (6/10)

Reaction notes

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