HuagongsheHuagongshe Chemistry Print Report · For research reference only
5-(4-Iodo-phenyl)-7-methylsulfanyl-pyrazolo[1,5-c]pyrimidine → 3-Bromo-5-(4-iodo-phenyl)-7-methylsulfanyl-pyrazolo[1,5-c]pyrimidine
Participants
| Role | Name | HCID | Charge |
|---|---|---|---|
| Reactant | 5-(4-Iodo-phenyl)-7-methylsulfanyl-pyrazolo[1,5-c]pyrimidine | HCID 67319419 | — |
| Reactant | HCID 86616047 | HCID 86616047 | — |
| Product | 3-Bromo-5-(4-iodo-phenyl)-7-methylsulfanyl-pyrazolo[1,5-c]pyrimidine | HCID 68426972 | — |
Reaction Steps
To a solution of 5-(4-iodo-phenyl)-7-methylsulfanyl-pyrazolo[1,5-c]pyrimidin (1000 mg) in chlorobenzene N-bromosuccinimide (730 mg) is added. The mixture is stirred for 1 hour then the chlorobenzene is evaporated. The residue is partitioned between ethylacetate and sodium-hydrogencarbonate (5%).
Provenance & Evidence
| DOI | 10.6084/m9.figshare.5104873.v1 |
|---|---|
| Patent number | US07745446B2 |
| Source dataset | uspto-grants-2010_06 |
| ORD ID | ord-3db5d3632b8b4049bcffda686f654c4d |
| Source note | uspto-grants-2010_06 |