HuagongsheHuagongshe Chemistry Print Report · For research reference only
Thiosemicarbazide → HCID 178527901, compound
Participants
| Role | Name | HCID | Charge |
|---|---|---|---|
| Reactant | Thiosemicarbazide | HCID 2723789 | — |
| Reactant | 1-(4-Iodo-phenyl)-5-methoxy-pent-4-ene-1,3-dione | HCID 67318321 | — |
| Solvent | Methanol | HCID 887 | — |
| Product | HCID 178527901 | HCID 178527901 | — |
Reaction Steps
A mixture of 1-(4-iodo-phenyl)-5-methoxy-pent-4-ene-1,3-dione (compound F1)(1.9 g) and thiosemicarbazide (5 g) in methanol (220 ml) is heated to reflux temperature. After the reaction is completed the solid is filtered and washed with methanol. The filtrate with the product is purified by flash silica gel chromatography.
Provenance & Evidence
| DOI | 10.6084/m9.figshare.5104873.v1 |
|---|---|
| Patent number | US07745446B2 |
| Source dataset | uspto-grants-2010_06 |
| ORD ID | ord-1a283ebeecc94dc18563be03e16f73f1 |
| Source note | uspto-grants-2010_06 |