Hydrochloric Acid → HCID 59436460, compound

Participants

Reaction Steps

To a solution of (2S,4S)-tert-butyl 2-(5-fluorothiazol-2-ylcarbamoyl)-4-hydroxypyrrolidine-1-carboxylate (1.42 g, 4.29 mmol) in MeOH (40 mL) was added 4N HCl in dioxane (10.71 mL, 42.9 mmol). The reaction mixture was stirred at RT for 2 h and concentrated. The residue was used for the next step without purification. LC/MS [M+H]+: 232; Ret time (Method F): 0.51 min.

Provenance & Evidence