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HuagongsheHuagongshe Chemistry Print Report · For research reference only
HRID 1961399Generated: October 30, 2026

Trifluoroacetic acid → HCID 59436393, compound

https://huagongshe.com/reaction/1961399

Reaction equation

Participants

RoleNameHCIDCharge
ReactantTrifluoroacetic acidHCID 6422—
ReactantHCID 59436342HCID 59436342—
SolventDichloromethaneHCID 6344—
ProductHCID 59436393HCID 59436393—

Reaction Steps

To a solution of (2S,4S)-tert-butyl 4-hydroxy-2-methyl-2-(thiazol-2-ylcarbamoyl)pyrrolidine-1-carboxylate (0.49 g, 1.5 mmol) in CH2Cl2 was added TFA (1 ml, excess). The reaction mixture was stirred at RT for 14 h and concentrated. The residue was used for the next step without purification. LC/MS [M+H]+: 228; Ret time (Method F): 0.46 min.

Provenance & Evidence

DOI10.6084/m9.figshare.5104873.v1
Patent numberUS08415340B2
Source datasetuspto-grants-2013_04
ORD IDord-ded2813ce1f64aa29808ad4871cd79c2
Source noteuspto-grants-2013_04