(S)-1-tert-butyl 2-methyl 2,4,4-trimethylpyrrolidine-1,2-dicarboxylate → (S)-Methyl 1-(4-chloro-6-(5-cyclopropyl-1H-pyrazol-3-ylamino)-1,3,5-triazin-2-yl)-2,4,4-trimethylpyrrolidine-2-carboxylate

HRID 1961405Notes

Reaction equation

Cl[C:2]1[N:7]=[C:6]([Cl:8])[N:5]=[C:4]([NH:9][C:10]2[NH:14][N:13]=[C:12]([CH:15]3[CH2:17][CH2:16]3)[CH:11]=2)[N:3]=1.[CH3:18][C@@:19]1([C:33]([O:35][CH3:36])=[O:34])[CH2:23][C:22]([CH3:25])([CH3:24])[CH2:21][N:20]1C(OC(C)(C)C)=O.ClC1N=C(NC2NN=C(C3CC3)C=2)N=C(N2CCC[C@@]2(C)C(NC2C=NC(F)=CC=2)=O)N=1>>[Cl:8][C:6]1[N:5]=[C:4]([NH:9][C:10]2[CH:11]=[C:12]([CH:15]3[CH2:17][CH2:16]3)[NH:13][N:14]=2)[N:3]=[C:2]([N:20]2[CH2:21][C:22]([CH3:24])([CH3:25])[CH2:23][C@@:19]2([CH3:18])[C:33]([O:35][CH3:36])=[O:34])[N:7]=1