(S)-1-tert-butyl 2-methyl 2,4,4-trimethylpyrrolidine-1,2-dicarboxylate → (S)-Methyl 1-(4-chloro-6-(5-cyclopropyl-1H-pyrazol-3-ylamino)-1,3,5-triazin-2-yl)-2,4,4-trimethylpyrrolidine-2-carboxylate

Participants

Role	Name	HCID	Charge
Reactant	(S)-1-tert-butyl 2-methyl 2,4,4-trimethylpyrrolidine-1,2-dicarboxylate	HCID 68474517	—
Reactant	HCID 178431741	HCID 178431741	—
Reactant	HCID 178478357	HCID 178478357	—
Product	(S)-Methyl 1-(4-chloro-6-(5-cyclopropyl-1H-pyrazol-3-ylamino)-1,3,5-triazin-2-yl)-2,4,4-trimethylpyrrolidine-2-carboxylate	HCID 59436414	—

Compound 106E was prepared from 1A and 106D as described for 1C: LC/MS [M+H]+: 406/408; Ret time (Method F): 3.55 min.