Back
HuagongsheHuagongshe Chemistry Print Report · For research reference only
HRID 1961414Generated: November 1, 2026

(1S,3S,5S)-tert-Butyl 3-(pyrazin-2-ylcarbamoyl)-2-azabicyclo[3.1.0]hexane-2-carboxylate → (1S,3S,5S)-N-(Pyrazin-2-yl)-2-azabicyclo[3.1.0]hexane-3-carboxamide

https://huagongshe.com/reaction/1961414

Reaction equation

Participants

RoleNameHCIDCharge
Reactant(1S,3S,5S)-tert-Butyl 3-(pyrazin-2-ylcarbamoyl)-2-azabicyclo[3.1.0]hexane-2-carboxylateHCID 59436392—
ReactantHCID 178522397HCID 178522397—
Product(1S,3S,5S)-N-(Pyrazin-2-yl)-2-azabicyclo[3.1.0]hexane-3-carboxamideHCID 59436362—

Reaction Steps

Compound 121C was prepared starting from 121B using the procedure as described in 65C. LC/MS [M+H]+: 205; Ret time (Method C): 0.70 min.

Provenance & Evidence

DOI10.6084/m9.figshare.5104873.v1
Patent numberUS08415340B2
Source datasetuspto-grants-2013_04
ORD IDord-7aa7cdffd4a64620b2729d72dafd3fcd
Source noteuspto-grants-2013_04