HCID 57289411, compound → HCID 582382, compound

HRID 1961424Notes

Reaction equation

HRID 1961424 reaction equation
[C:1]1([C:7]2[CH:14]=[CH:13][C:10]([C:11]#[N:12])=[CH:9][CH:8]=2)[CH2:6][CH2:5][CH2:4][CH2:3][CH:2]=1>CCO.[Pd]>[CH:1]1([C:7]2[CH:8]=[CH:9][C:10]([C:11]#[N:12])=[CH:13][CH:14]=2)[CH2:2][CH2:3][CH2:4][CH2:5][CH2:6]1

Participants

4

Reactant 1

HCID 57289411HCID 57289411, compound

Product 1

HCID 582382HCID 582382, compound

Reagents, catalysts & solvents 2

HCID 23938PalladiumCatalystHCID 702EthanolSolvent

Procedure

4-Cyclohexenylbenzonitrile (404 mg, 2.2 mmol) was dissolved in 15 ml EtOH and 40 mg 10% Pd/C was added. The reaction mixture was stirred under H2 at 3.0 atm. over night at room temperature. The mixture was filtered through celite with EtOAc washing. The filtrate was concentrated and the crude product 350 mg (86%) was used directly in the next step.

Workup

  1. filtrationThe mixture was filtered through celite with EtOAc washing
  2. concentrationThe filtrate was concentrated

Sources & evidence

ORD record
ord-869b93e70902403dac3b09cc5d24e630
Source dataset
uspto-grants-2013_04
Patent number
US08415333B2

Reaction notes

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