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HRID1961468

反应详情

EQUATION

反应方程式

HRID 1961468 的结构方程式

REACTANTS

反应物

2
结构：CCOC(=O)c1c(C)nc2ncccc2c1Cl
HCID66633913

未命名化合物

结构：Cc1[nH]c2ncccc2c(=O)c1C(=O)NCc1cccc(C(F)(F)F)c1
HCID66745469

未命名化合物

PRODUCTS

生成物

1
结构：Cc1nc2ncccc2c(Cl)c1C(=O)NCc1cccc(C(F)(F)F)c1
HCID66746089

未命名化合物

收率 59%

PROCEDURE

实验过程

This substance was synthesized from 2-Methyl-4-oxo-N-(3-(trifluoromethyl)benzyl)-1,4-dihydro-1,8-naphthyridine-3-carboxamide (130.0 mg, 0.36 mmol) following the same procedure used for ethyl 4-chloro-2-methyl-1,8-naphthyridine-3-carboxylate. Purification was done by flash chromatography (EtOAc/MeOH 100:0→96:4) giving 80.0 mg (59%) of the title compound.

WORKUP

后处理

  1. customPurification