HuagongsheHuagongshe Chemistry Print Report · For research reference only
Ether hydrochloride → (4-Azido-3-iodophenyl)methanamine hydrochloride
Participants
| Role | Name | HCID | Charge |
|---|---|---|---|
| Reactant | Ether hydrochloride | HCID 10953452 | — |
| Reactant | tert-Butyl 4-azido-3-iodobenzylcarbamate | HCID 86661980 | — |
| Product | (4-Azido-3-iodophenyl)methanamine hydrochloride | HCID 86661981 | 45% |
Reaction Steps
tert-Butyl 4-azido-3-iodobenzylcarbamate (936.0 mg, 2.5 mmol) was dissolved in Et2O.HCl (2.0 N in Et2O) (10 ml) was added to the solution. The mixture was stirred at r.t. overnight. The solvent was removed under vacuum and the residue washed with a mixture of CH2Cl2 and MeOH (8:2) affording 350 mg (45%) of the title compound.
Provenance & Evidence
| DOI | 10.6084/m9.figshare.5104873.v1 |
|---|---|
| Patent number | US08415333B2 |
| Source dataset | uspto-grants-2013_04 |
| ORD ID | ord-373f551e086a4231bdfd939c8284ff61 |
| Source note | uspto-grants-2013_04 |