Back
HuagongsheHuagongshe Chemistry Print Report · For research reference only
HRID 1961511Generated: October 26, 2026

3-Amino-1-phenyl-1H-pyrazole-4-carbonitrile → 3-({4-[(4-methylpiperazin-1-yl)carbonyl]phenyl}amino)-1-phenyl-1H-pyrazole-4-carbonitrile

https://huagongshe.com/reaction/1961511

Reaction equation

Participants

RoleNameHCIDCharge
Reactant3-Amino-1-phenyl-1H-pyrazole-4-carbonitrileHCID 2774249—
Reactant1-(4-Bromobenzoyl)-4-methylpiperazineHCID 4464352—
Product3-({4-[(4-methylpiperazin-1-yl)carbonyl]phenyl}amino)-1-phenyl-1H-pyrazole-4-carbonitrileHCID 67253450—

Reaction Steps

3-({4-[(4-methylpiperazin-1-yl)carbonyl]phenyl}amino)-1-phenyl-1H-pyrazole-4-carbonitrile was prepared according to the general procedure in Example 7 Step 2 using 3-amino-1-phenyl-1H-pyrazole-4-carbonitrile (50 mg, 0.271 mmol) and 1-(4-bromobenzoyl)-4-methylpiperazine (77 mg, 0.271 mmol) as the starting materials.

Provenance & Evidence

DOI10.6084/m9.figshare.5104873.v1
Patent numberUS08415346B2
Source datasetuspto-grants-2013_04
ORD IDord-bbd16f8b5d0d4c4db9701dc7b097f693
Source noteuspto-grants-2013_04