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HuagongsheHuagongshe Chemistry Print Report · For research reference only
HRID 1961515Generated: October 25, 2026

3-Amino-1-phenyl-1H-pyrazole-4-carbonitrile → 3-{[4-(1-hydroxy-1-methylethyl)phenyl]amino}-1-phenyl-1H-pyrazole-4-carbonitrile

https://huagongshe.com/reaction/1961515

Reaction equation

Participants

RoleNameHCIDCharge
Reactant3-Amino-1-phenyl-1H-pyrazole-4-carbonitrileHCID 2774249—
Reactant2-(4-Iodophenyl)propan-2-olHCID 53996144—
Product3-{[4-(1-hydroxy-1-methylethyl)phenyl]amino}-1-phenyl-1H-pyrazole-4-carbonitrileHCID 67255498—

Reaction Steps

3-{[4-(1-hydroxy-1-methylethyl)phenyl]amino}-1-phenyl-1H-pyrazole-4-carbonitrile was prepared according to the general procedure in Example 11 Step 1 using 3-amino-1-phenyl-1H-pyrazole-4-carbonitrile (70 mg, 0.380 mmol) and 2-(4-iodophenyl)propan-2-ol (100 mg, 0.380 mmol) as the starting materials.

Provenance & Evidence

DOI10.6084/m9.figshare.5104873.v1
Patent numberUS08415346B2
Source datasetuspto-grants-2013_04
ORD IDord-c2b45f6173824979af7182163e367d77
Source noteuspto-grants-2013_04