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HuagongsheHuagongshe Chemistry Print Report · For research reference only
HRID 1961666Generated: October 31, 2026

1,3-Benzodioxole-5-carboxylic acid → HCID 178523663, compound

https://huagongshe.com/reaction/1961666

Reaction equation

Participants

RoleNameHCIDCharge
Reactant1,3-Benzodioxole-5-carboxylic acidHCID 7196—
ReactantHCID 178478716HCID 178478716—
ProductHCID 178523663HCID 178523663—

Reaction Steps

From {1-[2-(trans-4-amino-cyclohexyl)-ethyl]-piperidin-4-yl}-(5-chloro-thiophen-2-yl)-methanone dihydrochloride (100 mg) and benzo[1,3]dioxole-5-carboxylic acid (45 mg) by procedure C. Yield: 62 mg (52%). Off-white solid. MS (m/z): 503.2 ([M+H]+).

Provenance & Evidence

DOI10.6084/m9.figshare.5104873.v1
Patent numberUS08415350B2
Source datasetuspto-grants-2013_04
ORD IDord-be551c9504f94002b617036f392ff4c6
Source noteuspto-grants-2013_04