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HRID1962438

反应详情

EQUATION

反应方程式

HRID 1962438 的结构方程式

REACTANTS

反应物

3
结构：CC(C)(C)OC(=O)N[C@H]1CCCNC1
HCID1514171

(S)-3-Boc-aminopiperidine

C10H20N2O2

结构：CC(C)(C)OC(=O)NC1CCCNC1
HCID4233041

3-Boc-aminopiperidine

C10H20N2O2

结构：CC(C)(C)OC(=O)NC1CCCN(S(=O)(=O)c2cccc3cncc(Cl)c23)C1
HCID67242669

未命名化合物

2 次

PRODUCTS

生成物

2
结构：Cl
HCID313

Hydrochloric Acid

ClH

结构：NC1CCCN(S(=O)(=O)c2cccc3cncc(Cl)c23)C1
HCID67242690

未命名化合物

PROCEDURE

实验过程

3-(tert-Butoxycarbonylamino)-1-(4-chloro-5-isoquinolinesulfonyl)piperidine (Intermediate 18) can be prepared by using 3-(tert-butoxycarbonylamino)piperidine in the method of Example 21-1, Step A instead of (S)-3-(tert-butoxycarbonylamino)piperidine, and then used in the method of Step B in a similar manner to obtain the title compound as hydrochloride.