HuagongsheHuagongshe Chemistry Print Report · For research reference only
(1R,2R)-2-aminocyclopentan-1-ol hydrochloride → HCID 49803585, compound
Participants
| Role | Name | HCID | Charge |
|---|---|---|---|
| Reactant | (1R,2R)-2-aminocyclopentan-1-ol hydrochloride | HCID 12886906 | — |
| Reactant | 5-(5-Methyl-3-pyridin-2-yl-isoxazol-4-ylmethoxy)-pyridine-2-carboxylic acid | HCID 66644648 | — |
| Product | HCID 49803585 | HCID 49803585 | 78% |
Reaction Steps
As described for example 7, 5-(5-methyl-3-pyridin-2-yl-isoxazol-4-ylmethoxy)-pyridine-2-carboxylic acid (100 mg, 0.32 mmol) was converted, using trans-2-aminocyclopentanol hydrochloride instead of isopropylamine, to the title compound (100 mg, 78%), which was obtained as a white solid. MS: m/e=395.1 [M+H]+.
Provenance & Evidence
| DOI | 10.6084/m9.figshare.5104873.v1 |
|---|---|
| Patent number | US08415379B2 |
| Source dataset | uspto-grants-2013_04 |
| ORD ID | ord-a899b961adb4457fbe6bae2b806d6256 |
| Source note | uspto-grants-2013_04 |