Acetate → 5-(2-Oxopyrrolidin-1-yl)-biphenyl-3-carboxylic Acid Methyl Ester

HRID 196339Notes

Reaction equation

HRID 196339 reaction equation
[C:18](=[O:19])([O-:20])[O-:21].[CH3:1][O:2][C:3]([c:4]1[cH:5][c:6]([Br:16])[cH:7][c:8]([N:10]2[C:11](=[O:15])[CH2:12][CH2:13][CH2:14]2)[cH:9]1)=[O:17].[CH3:33][O:34][CH2:35][CH2:36][O:37][CH3:38].[Na+:22].[Na+:23].[O-:40][C:41]([CH3:42])=[O:43].[O-:44][C:45]([CH3:46])=[O:47].[Pd+2:39].[c:24]1([B:30]([OH:31])[OH:32])[cH:25][cH:26][cH:27][cH:28][cH:29]1>>[CH3:1][O:2][C:3]([c:4]1[cH:5][c:6](-[c:24]2[cH:25][cH:26][cH:27][cH:28][cH:29]2)[cH:7][c:8]([N:10]2[C:11](=[O:15])[CH2:12][CH2:13][CH2:14]2)[cH:9]1)=[O:17]

Participants

8

Reactant 7

HCID 175Acetate2×HCID 923Sodium ion2×HCID 80711,2-DimethoxyethaneHCID 19660Carbonate IonHCID 66827Phenylboronic AcidHCID 105144Allyl(1,3-bis(2,6-diisopropylphenyl)imidazol-2-ylidene)chloropalladium(II)HCID 22253055Methyl 3-bromo-5-(2-oxopyrrolidin-1-yl)benzoate

Product 1

HCID 695897705-(2-Oxopyrrolidin-1-yl)-biphenyl-3-carboxylic Acid Methyl Ester

Sources & evidence

ORD record
ord-5a176a0622bb4cb8aa49f817dbd1a35c
Source dataset
Training data from https://doi.org/10.1039/C8SC04228D (6/10)

Reaction notes

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