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HuagongsheHuagongshe Chemistry Print Report · For research reference only
HRID 196344Generated: October 28, 2026

Dimethylformamide → 4-[3-(4-Chlorobenzyl)-6-(2,2-difluoroethoxy)-2,4-dioxo-3,4-dihydroquinazolin-1(2H)-yl]piperidine-1-carbaldehyde

https://huagongshe.com/reaction/196344

Reaction equation

Participants

RoleNameHCIDCharge
ReactantDimethylformamideHCID 6228—
ReactantEthyl AcetateHCID 8857—
ReactantCarbonate IonHCID 19660—
Reactant1-(Bromomethyl)-4-chlorobenzeneHCID 69329—
ReactantCesium cationHCID 104967—
Reactant4-[6-(2,2-Difluoroethoxy)-2,4-dioxo-3,4-dihydroquinazolin-1(2H)-yl]piperidine-1-carbaldehydeHCID 25253349—
Product4-[3-(4-Chlorobenzyl)-6-(2,2-difluoroethoxy)-2,4-dioxo-3,4-dihydroquinazolin-1(2H)-yl]piperidine-1-carbaldehydeHCID 25253500—

Provenance & Evidence

DOI10.1039/C8SC04228D
Source datasetTraining data from https://doi.org/10.1039/C8SC04228D (6/10)
ORD IDord-e2194981dd6b493cb36aa5f8f44826b4
Source noteTraining data from https://doi.org/10.1039/C8SC04228D (6/10)