Boron tribromide → HCID 67240920, compound

HRID 1963660Notes

Reaction equation

HRID 1963660 reaction equation
[C:1]1([S:7]([C:10]2[CH:15]=[CH:14][C:13]([C:16]3[CH:21]=[C:20]([Cl:22])[CH:19]=[CH:18][C:17]=3[O:23]CC3C=CC=CC=3)=[CH:12][CH:11]=2)(=[O:9])=[O:8])[CH:6]=[CH:5][CH:4]=[CH:3][CH:2]=1.B(Br)(Br)Br>C(Cl)Cl>[Cl:22][C:20]1[CH:21]=[C:16]([C:13]2[CH:12]=[CH:11][C:10]([S:7]([C:1]3[CH:6]=[CH:5][CH:4]=[CH:3][CH:2]=3)(=[O:9])=[O:8])=[CH:15][CH:14]=2)[C:17]([OH:23])=[CH:18][CH:19]=1

Participants

4

Reactant 2

HCID 25134Boron tribromideHCID 67238608HCID 67238608, compound

Product 1

HCID 67240920HCID 67240920, compound

Reagents, catalysts & solvents 1

HCID 6344DichloromethaneSolvent2×

Procedure

The product from example 1 step (i) (0.9 g) was treated with 1.0M boron tribromide in DCM (3.10 ml) in dry DCM (20 ml) and stirred at room temperature for 1 hour. The mixture was quenched in ice water and extracted with DCM, dried (MgSO4) and concentrated under reduced pressure to give the sub-title compound, yield 0.9 g

Workup

  1. customThe mixture was quenched in ice water
  2. extractionextracted with DCM
  3. dry with materialdried (MgSO4)
  4. concentrationconcentrated under reduced pressure

Sources & evidence

ORD record
ord-5fe8969429364903998ca379cbf01d84
Source dataset
uspto-grants-2013_04
Patent number
US08415394B2

Reaction notes

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