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HuagongsheHuagongshe Chemistry Print Report · For research reference only
HRID 1963802Generated: October 29, 2026

Benzaldehyde → N-Benzylidene(piperidin-4-yl)methanamine

https://huagongshe.com/reaction/1963802

Reaction equation

Participants

RoleNameHCIDCharge
ReactantBenzaldehydeHCID 240—
Reactant4-(Aminomethyl)piperidineHCID 23527—
SolventTolueneHCID 1140—
ProductN-Benzylidene(piperidin-4-yl)methanamineHCID 11820173—

Reaction Steps

Benzaldehyde (4.6 g; 0.044 mol) was added dropwise to a solution of 4-aminomethylpiperidine (5.0 g; 0.044 mol) in toluene (20 ml). The solution thus obtained was stirred for 3 h at room temperature. Then the solvent was removed by evaporation at reduced pressure and the residue was taken up twice with toluene to give the desired product that was used as such without further purification.

Provenance & Evidence

DOI10.6084/m9.figshare.5104873.v1
Patent numberUS08415476B2
Source datasetuspto-grants-2013_04
ORD IDord-44fbf3dbd5fd4a169f29a44f7e72412c
Source noteuspto-grants-2013_04