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HuagongsheHuagongshe Chemistry Print Report · For research reference only
HRID 1963970Generated: October 27, 2026

(4-((5'-chloro-2'-fluoro-2,4'-bipyridin-6-ylamino)methyl)tetrahydro-2H-pyran-4-yl)methanol → HCID 178495712, compound

https://huagongshe.com/reaction/1963970

Reaction equation

Participants

RoleNameHCIDCharge
Reactant(4-((5'-chloro-2'-fluoro-2,4'-bipyridin-6-ylamino)methyl)tetrahydro-2H-pyran-4-yl)methanolHCID 66937045—
ReactantHCID 178495714HCID 178495714—
ProductHCID 178495712HCID 178495712—

Reaction Steps

Following the same procedure as in Example 1b using (4-((5′-chloro-2′-fluoro-2,4′-bipyridin-6-ylamino)methyl)tetrahydro-2H-pyran-4-yl)methanol (from step 4) and trans-N1-((R)-1-methoxypropan-2-yl)cyclohexane-1,4-diamine, the desired product was obtained. LCMS (m/z): 518.2 (MH+), retention time=0.47 min.

Provenance & Evidence

DOI10.6084/m9.figshare.5104873.v1
Patent numberUS08415381B2
Source datasetuspto-grants-2013_04
ORD IDord-78e5da9d2eda40d787af739ba711a733
Source noteuspto-grants-2013_04