HuagongsheHuagongshe Chemistry Print Report · For research reference only
2-(2-((4-Chloro-2-(methoxycarbonyl)phenyl)amino)-2-oxoethoxy)acetic acid → 5-Chloro-2-[((2-oxo-2-[(3',4,5'-trimethylbiphenyl-3-yl)amino]ethoxy)acetyl)amino]benzoic acid
Participants
| Role | Name | HCID | Charge |
|---|---|---|---|
| Reactant | 2-(2-((4-Chloro-2-(methoxycarbonyl)phenyl)amino)-2-oxoethoxy)acetic acid | HCID 51039954 | — |
| Reactant | 3',4,5'-Trimethylbiphenyl-3-amine | HCID 61025272 | — |
| Product | 5-Chloro-2-[((2-oxo-2-[(3',4,5'-trimethylbiphenyl-3-yl)amino]ethoxy)acetyl)amino]benzoic acid | HCID 44250943 | — |
Reaction Steps
Using the same method as in Example 1-(ii), 3′,4,5′-trimethylbiphenyl-3-amine was reacted with the (2-([4-chloro-2-(methoxycarbonyl)phenyl]amino)-2-oxoethoxy)acetic acid obtained in Example 1-(i) to give 5-chloro-2-[((2-oxo-2-[(3′,4,5′-trimethylbiphenyl-3-yl)amino]ethoxy)acetyl)amino]benzoic acid.methyl ester (yield: 91%).
Provenance & Evidence
| DOI | 10.6084/m9.figshare.5104873.v1 |
|---|---|
| Patent number | US08415479B2 |
| Source dataset | uspto-grants-2013_04 |
| ORD ID | ord-0f08190518044f79ae0752fdaf2ed9a6 |
| Source note | uspto-grants-2013_04 |