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HuagongsheHuagongshe Chemistry Print Report · For research reference only
HRID 1963997Generated: October 25, 2026

3-Bromoaniline → 2-[((2-[(3-Bromophenyl)amino]-2-oxoethoxy)acetyl)amino]-5-chlorobenzoic acid

https://huagongshe.com/reaction/1963997

Reaction equation

Participants

RoleNameHCIDCharge
Reactant3-BromoanilineHCID 11562—
Reactant2-(2-((4-Chloro-2-(methoxycarbonyl)phenyl)amino)-2-oxoethoxy)acetic acidHCID 51039954—
Product2-[((2-[(3-Bromophenyl)amino]-2-oxoethoxy)acetyl)amino]-5-chlorobenzoic acidHCID 86653349—

Reaction Steps

Using the same method as in Example 1-(ii), 3-bromoaniline was reacted with the (2-([4-chloro-2-(methoxycarbonyl)phenyl]amino)-2-oxoethoxy)acetic acid obtained in Example 1-(i) to give 2-[((2-[(3-bromophenyl)amino]-2-oxoethoxy)acetyl)amino]-5-chlorobenzoic acid.methyl ester (yield: 81%)

Provenance & Evidence

DOI10.6084/m9.figshare.5104873.v1
Patent numberUS08415479B2
Source datasetuspto-grants-2013_04
ORD IDord-d64b7a01ac364715a34485e636e1167f
Source noteuspto-grants-2013_04