HuagongsheHuagongshe Chemistry Print Report · For research reference only
5-([4-Chloro-2-(methoxycarbonyl)phenyl]amino)-5-oxopentanoic acid → 5-Chloro-2-[(5-(ethyl[5-(furan-3-yl)-2-methylphenyl]amino)-5-oxopentanoyl)amino]benzoic acid
Participants
| Role | Name | HCID | Charge |
|---|---|---|---|
| Reactant | 5-([4-Chloro-2-(methoxycarbonyl)phenyl]amino)-5-oxopentanoic acid | HCID 51040152 | — |
| Reactant | N-ethyl-5-(furan-3-yl)-2-methylaniline | HCID 66877311 | — |
| Product | 5-Chloro-2-[(5-(ethyl[5-(furan-3-yl)-2-methylphenyl]amino)-5-oxopentanoyl)amino]benzoic acid | HCID 44251302 | — |
Reaction Steps
Using the same method as in Example 15-(i), N-ethyl-5-(furan-3-yl)-2-methylaniline was reacted with the 5-([4-chloro-2-(methoxycarbonyl)phenyl]amino)-5-oxopentanoic acid obtained in Example 31-(i) to give 5-chloro-2-[(5-(ethyl[5-(furan-3-yl)-2-methylphenyl]amino)-5-oxopentanoyl)amino]benzoic acid.methyl ester (yield: 58%).
Provenance & Evidence
| DOI | 10.6084/m9.figshare.5104873.v1 |
|---|---|
| Patent number | US08415479B2 |
| Source dataset | uspto-grants-2013_04 |
| ORD ID | ord-0bf303f18936430e9f1e8692aff08e3f |
| Source note | uspto-grants-2013_04 |