HuagongsheHuagongshe Chemistry Print Report · For research reference only
1-(3,3-Dimethyl-6-nitroindolin-1-yl)ethanone → 1-(6-Amino-3,3-dimethylindolin-1-yl)ethanone
Participants
| Role | Name | HCID | Charge |
|---|---|---|---|
| Reactant | 1-(3,3-Dimethyl-6-nitroindolin-1-yl)ethanone | HCID 16127418 | — |
| Catalyst | Palladium | HCID 23938 | — |
| Solvent | Ethanol | HCID 702 | — |
| Product | 1-(6-Amino-3,3-dimethylindolin-1-yl)ethanone | HCID 21865176 | 99.4% |
Reaction Steps
A mixture of 1-(3,3-dimethyl-6-nitroindolin-1-yl)ethanone (300 mg), 10% Pd—C (50 mg), and EtOH (50 mL) was stirred under hydrogen atmosphere (1 atm) for 3 h. The catalyst was filtered out and the filtrate was concentrated to give a light yellow solid (260 mg).
Provenance & Evidence
| DOI | 10.6084/m9.figshare.5104873.v1 |
|---|---|
| Patent number | US07745451B2 |
| Source dataset | uspto-grants-2010_06 |
| ORD ID | ord-8ecd7fd50f4d41ec96250d47380662a3 |
| Source note | uspto-grants-2010_06 |