2,4,6-Trimethylpyridine → 3-(4,4-Dimethyl-8-hydroxy-2-oxo-1,4-dihydro-2H-3,1-benzoxazin-6-yl)-5-fluorobenzonitrile
Reaction equation
[CH3:1][C:2]1([CH3:24])[O:3][C:4](=[O:23])[NH:5][c:6]2[c:7]1[cH:8][c:9](-[c:14]1[cH:15][c:16]([C:17]#[N:18])[cH:19][c:20]([F:22])[cH:21]1)[cH:10][c:11]2[O:12][CH3:13].[I-:25].[Li+:26].[n:27]1[c:28]([CH3:29])[cH:30][c:31]([CH3:32])[cH:33][c:34]1[CH3:35]>>[CH3:1][C:2]1([CH3:24])[O:3][C:4](=[O:23])[NH:5][c:6]2[c:7]1[cH:8][c:9](-[c:14]1[cH:15][c:16]([C:17]#[N:18])[cH:19][c:20]([F:22])[cH:21]1)[cH:10][c:11]2[OH:12]Participants
5
Sources & evidence
- ORD record
- ord-b5ebe4b9573b405c98774ed84a276e08
- Source dataset
- Training data from https://doi.org/10.1039/C8SC04228D (6/10)
Reaction notes
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