Participants
| Role | Name | HCID | Charge |
|---|
| Reactant | Iodine | HCID 807 | — |
| Reactant | Potassium Carbonate | HCID 11430 | — |
| Reactant | Potassium bisulfate | HCID 516920 | — |
| Reactant | HCID 178516518 | HCID 178516518 | — |
| Solvent | Water | HCID 962 | — |
| Product | HCID 178516519 | HCID 178516519 | — |
Reaction Steps
A mixture of 2,4-dihydroxypyridine (1.0 eq), K2CO3 (1.0 eq), and water was stirred at 100° C. so that it became homogeneous. With continued stirring and heating, I2 (1.0 eq) was added in portions, causing the evolution of gas. When the solid I2 was consumed, the mixture was cooled and acidified with aqueous KHSO4 (1.0 eq), generating a precipitate. The precipitate was collected by filtration, rinsed with water, and stored under high vacuum, to give 2,4-dihydroxy-3-iodopyridine.
Provenance & Evidence
| DOI | 10.6084/m9.figshare.5104873.v1 |
|---|
| Patent number | US07745454B2 |
|---|
| Source dataset | uspto-grants-2010_06 |
|---|
| ORD ID | ord-c55d733421a444529c3510bfaeac415c |
|---|
| Source note | uspto-grants-2010_06 |
|---|
