Bromobenzene → HCID 66657262, compound

HRID 1966021Notes

Reaction equation

HRID 1966021 reaction equation
[CH2:1]([N:8]1[CH2:12][CH2:11][C@H:10]([NH2:13])[CH2:9]1)[C:2]1[CH:7]=[CH:6][CH:5]=[CH:4][CH:3]=1.Br[C:15]1[CH:20]=[CH:19][CH:18]=[CH:17][CH:16]=1>>[CH2:1]([N:8]1[CH2:12][CH2:11][C@H:10]([NH:13][C:15]2[CH:20]=[CH:19][CH:18]=[CH:17][CH:16]=2)[CH2:9]1)[C:2]1[CH:3]=[CH:4][CH:5]=[CH:6][CH:7]=1

Participants

3

Reactant 2

HCID 7961BromobenzeneHCID 1519353(3S)-(+)-1-Benzyl-3-aminopyrrolidine

Product 1

HCID 66657262HCID 66657262, compound

Procedure

((S)-1-benzylpyrrolidin-3-yl)-phenylamine was synthesized using (S)-1-benzylpyrrolidin-3-ylamine and bromobenzene in the same manner as in Reference Example 3.

Sources & evidence

ORD record
ord-94ac7344664045b9aa7a0adb64c2f8fe
Source dataset
uspto-grants-2013_04
Patent number
US08420623B2

Reaction notes

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