HuagongsheHuagongshe Chemistry Print Report · For research reference only
Triethylamine → HCID 57820161, compound
Participants
| Role | Name | HCID | Charge |
|---|---|---|---|
| Reactant | Triethylamine | HCID 8471 | — |
| Reactant | 4-Nitrophenyl formate | HCID 74628 | — |
| Reactant | HCID 57820361 | HCID 57820361 | — |
| Solvent | Tetrahydrofuran | HCID 8028 | — |
| Product | HCID 57820161 | HCID 57820161 | — |
Reaction Steps
The compound is obtained by treating [7-(3,5-difluoro-4-morpholin-4-ylmethyl-phenyl)-7H-pyrrolo[2,3-d]pyrimidin-2-yl]-(4-methyl-3-piperazin-1-ylmethyl-phenyl)-amine (Example 332) with formic acid 4-nitro-phenyl ester in presence of triethylamine in THF. HPLC: tR=6.84 min (Method B); MS-ES: (M+H)+=562
Provenance & Evidence
| DOI | 10.6084/m9.figshare.5104873.v1 |
|---|---|
| Patent number | US08420657B2 |
| Source dataset | uspto-grants-2013_04 |
| ORD ID | ord-f668ecaa588f448b89fbaa0ebea4b37c |
| Source note | uspto-grants-2013_04 |