HuagongsheHuagongshe Chemistry Print Report · For research reference only
Methanesulfonyl chloride → N-[2-(4-{[(S)-((S)-1-Allylpiperidin-2-yl)-phenylmethyl]-amino}-2-methylquinolin-8-yloxy)ethyl]methanesulfonamide
Participants
| Role | Name | HCID | Charge |
|---|---|---|---|
| Reactant | Methanesulfonyl chloride | HCID 31297 | — |
| Reactant | [(S)-((S)-1-Allylpiperidin-2-yl)-phenyl methyl]-[8-(2-aminoethoxy)-2-methylquinolin-4-yl]-amine | HCID 59474789 | — |
| Product | N-[2-(4-{[(S)-((S)-1-Allylpiperidin-2-yl)-phenylmethyl]-amino}-2-methylquinolin-8-yloxy)ethyl]methanesulfonamide | HCID 59474734 | — |
Reaction Steps
Preparation was made using a similar procedure as described in example 21. Starting materials were [(S)—((S)-1-allylpiperidin-2-yl)-phenylmethyl]-[8-(2-aminoethoxy)-2-methylquinolin-4-yl]-amine (example 34) and methanesulfonyl chloride.
Provenance & Evidence
| DOI | 10.6084/m9.figshare.5104873.v1 |
|---|---|
| Patent number | US08420670B2 |
| Source dataset | uspto-grants-2013_04 |
| ORD ID | ord-6d7d3ecbd7a44d4fa9f1140f2afeb976 |
| Source note | uspto-grants-2013_04 |