反应详情

A solution of Intermediate 20 (1 g, 4.42 mmol) in methanol (20 ml) was hydrogenated in the presence of palladium on charcoal (10 mg, 10%) for 3 hours. The mixture was then filtered over Celite and the solvent removed under reduced pressure. The residue (0.91 g) was used in the next step without further purification.

1. filtrationThe mixture was then filtered over Celite
2. customthe solvent removed under reduced pressure
3. customThe residue (0.91 g) was used in the next step without further purification