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HRID1966633

反应详情

EQUATION

反应方程式

HRID 1966633 的结构方程式

REACTANTS

反应物

2
结构：Cc1cccc(C(F)(F)COCCCCCCBr)c1
HCID67245676

1-[2-[(6-Bromohexyl)oxy]-1,1-difluoroethyl]-3-methylbenzene

C15H21BrF2O

结构：O=C1c2ccccc2C(=O)N1CCCCCCOCC(F)(F)c1ccccc1
HCID67245867

2-[6-(2,2-Difluoro-2-phenylethoxy)hexyl]-1H-isoindole-1,3(2H)-dione

C22H23F2NO3

PRODUCTS

生成物

1
结构：Cc1cccc(C(F)(F)COCCCCCCN2C(=O)c3ccccc3C2=O)c1
HCID67246592

未命名化合物

收率 40%

PROCEDURE

实验过程

Obtained from Intermediate 30 (8.77 g, 26.2 mmol) by the procedure described in Intermediate 8. Purification by column chromatography with silica gel and methylene chloride as eluent gave the title compound (4.0 g, 40%) as oil.

WORKUP

后处理

  1. customPurification by column chromatography with silica gel and methylene chloride as eluent